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Saving Throws happen when your characters are trying to resist a negative Effect caused by Spells or Class Feature's abilities.
There are 6 types of Saving Throws, correspond to the number of Ability Scores:
- Strength Saving Throws
- Dexterity Saving Throws
- Constitution Saving Throws
- Intelligence Saving Throws
- Wisdom Saving Throws
- Charisma Saving Throws
Every Class offers at least 2 Saving Throws Proficiency.
When rolling Saving Throws, you roll: 
d20 + Saving Throw Proficiency Bonus (if available) + Ability Score Modifiers