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Involvement
Sister Vanessa is one of surgical assistants of Malus Thorm in the House of Healing. Along with three other Undead Nurses (Anya, Geanne and Hunna) she is trying to grasp the 'science' provided by the Shar's Scalpel and master all its ins and outs - literally, on a still alive patient.
When the party encounter Sister Vanessa, they won't be able to speak directly neither to her nor to other three sisters, because approaching the group immediately triggers the dialogue with Malus Thorm himself.
During the dialogue, the player may (among other options) convince Malus Thorm to order sisters kill one another or to order the nurses to operate on himself. Should the player choose the latter, Sister Vanessa will remain neutral after the surgeon's demise. She'll begin to wander around the auditorium, dropping philosophical phrases about patients, healing and Thorm's fate. If attacked afterwards, other Undead Nurses around will come to her aid.
Sister Vanessa is the only one of her colleagues that cannot be spoken to after Malus Thorm's final death. Instead, the player will see a Narrator line suggesting Vanessa either has nothing to say or is totally dumb.