Deadlier than Arsenic

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Protection from Energy.webp

Deadlier than Arsenic is a level 4 evocation spell. It is a variant of Kereska's Favour that allows its caster to imbue themselves with the power of poison and unlock resistances and spells associated with it. It is granted by Markoheshkir.


Embrace Kereska's poison to gain resistance to Damage TypesPoison damage. Your poison spells deal additional Damage TypesPoison damage equal to your proficiency bonus.

When you deal spell damage, inflict 2 turns[See Notes] of Poisoned Poisoned upon the target. While attuned to Kereska's poison you can cast Cloudkill Cloudkill and Ray of Sickness Ray of Sickness once each per short rest.

Cloudkill Cloudkill ()
Cast as a level 5 spell ( Recharge: Short rest.)
Ray of Sickness Ray of Sickness ()
Cast as a level 5 spell ( Recharge: Short rest.)


 Range: Self
Recharge: Short rest

At higher levels

Casting this spell at a higher level grants no additional benefit.

Condition: Vessel for Kereska's Poison

Vessel for Kereska's Poison Vessel for Kereska's Poison

Duration: Until Long rest

How to learn

Granted by the following items:

This spell is a variation of:
Kereska's Favour Kereska's Favour


  • The in-game tooltip says this effect inflicts Poisoned for 1 turn, but it actually inflicts it for 2 turns.
  • Applying Poisoned can only occur once per attack. A spell hitting multiple targets like Cloudkill Cloudkill will only apply the condition to a single target.
  • The version of Ray of Sickness Ray of Sickness granted by this spell matches the damage of a level 5 upcasted version (6d8Damage TypesPoison), but it only counts as a level 1 spell.