The Sharran Sanctuary is a Location found under Reithwin Town in the Shadow-Cursed Lands in Act Two.
How to Access the Sharran Sanctuary
In Reithwin Town, north of the 
Moonrise Towers waypoint, find the statue of Ketheric Thorm X: -152 Y: -30 and interact with the plaques in the following order: north, west, east.
This opens a hidden staircase on the south side of the statue that leads down into the sanctuary.
The Dark Lady's Ritual
Each of the three statues provides a unique Shar blessing until the next Long Rest:
- Dark Lady's Grace (+5 to Charisma)
- Dark Lady's Awareness (+5 to Wisdom)
- Dark Lady's Erudition (+5 to Intelligence)
A DC 14 
Saving throw for the corresponding Ability is required at each of the statues in order to receive the Dark Lady's blessing(s). Each blessing may only be obtained once.
Succeeding all three saving throws will open a door to a hidden chamber where a sacrificial ritual can be completed. Completing this ritual will reveal the scrolls and potions listed below (note: a Cleric of Shar can succeed at the ritual automatically).
Notable Loot
Notable items obtained in this location, whether looted, purchased, or obtained as a quest reward:
- In the hidden ritual chamber:
- Ritual Dagger of Shar (taking the dagger spawns a Charismatic Sentinel, Intelligent Sentinel and Wise Sentinel, and yields disapproval from Shadowheart)
- Additional loot revealed by completing the ritual: