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Owlbear Den
The Owlbear and her cub are found in the northwestern section of the cavern. The area can be approached either by continuing forward north then west from the cave entrance or via a slope north of the Selûne Shrine. Without using stealth, you'll be quickly noticed and forced to interact with the Owlbear mother, leading to or avoiding a fight. Details on possible interaction and tactics can be found here.
If a fight does break out and the cub survives, the party will get the choice to either spare it or finish it off while it eats its mother's remains. Sparing the cub is a critical choice if the party wants to have it become a camp follower. If the party attacked the Owlbear from stealth without activating the initial cut scene, the option to spare the cub will not be presented and the cub will keep attacking. In this case, if the party wishes to save the cub, then after killing the Owlbear (and Owlbear Mate in Honour mode) and grabbing any loot desired, the party will need to flee from combat without killing the cub. Then, after a long rest thee cub will appear in the Goblin camp. Beware that downing the cub with non-violent combat will not allow the party to gain it as a camp follower.
Another way to obtain the cub as a camp follower is to avoid the fight with the mother, after talking to her and retreating. Following your next long rest and returning to the cave, you will find the mother killed by some goblins, providing you easy access to the Owlbear Egg and the Head of a Broken Spear. After a period of time, the cub will join you at your camp
After the fight, there is a headless skeleton by the nest which has the 
The Oak Father's Embrace. Next to it is the valuable 
Owlbear Egg, worth 750 gold and provides 40 Camp Supplies, which can also be saved for the Steal a Githyanki Egg quest.
Selûne Shrine
The shrine is found inside the Cave Entrance to the Owlbear Nest by taking the first path to the southwest and moving down a Cragged Rock.
The peaceful shrine has a collection of offerings useful when dealing with the Owlbear, notably the 
Potion of Animal Speaking. A Gilded Chest is surrounded by a magical aura that will unleash a burst of magic upon interaction. DC 14 
Dexterity saving throw is required to avoid taking 4d6
Radiant damage.
To open the Gilded Chest, jump behind the Selûne statue. If you succeed at a passive 
DC 10 Perception check. check, you'll find a 
Selûnite Prayer Sheet which can be identified with a passive DC 15 History check. Read the prayer item next to the chest using anyone other than Shadowheart to successfully dispel the seal, rewarding 15 experience and triggering the Acolyte Inspiration, Her Gift of Silver. Alternative methods to open the chest without the prayer include opening it with a Cleric who worships Selûne or using the Knock spell. The chest holds the 
Moondrop Pendant, a note describing ancient Selunite rites, a silver necklace, and the unique 
Idol of Selûne that can make a interesting camp decoration.
If you try to take the items in the chest while Shadowheart is in the party, you will need to make a DC 15 Sleight of Hand check or risk losing Approval with her. That also can be avoided by putting the whole chest into the inventory of a character other than Shadowheart. If the chest is opened in the inventory, then Shadowheart won't notice it.
Related locations
Related quests
Notable loot
Notable items obtained in this location, whether looted, purchased, or obtained as a quest reward:
The Oak Father's Embrace (On the headless skeleton besides the nest.) X: -357 Y: -108
Owlbear Egg X: -357 Y: -112
Head of a Broken Spear (Found on the Owlbear, needed to create the Vision of the Absolute spear)
Moondrop Pendant (Inside the magically sealed chest at the Selûne Shrine) X: -328 Y: -136